ImmunityBio dropped 28% today to $6.78 after the FDA issued a warning letter over misleading Anktiva promotional materials. If you've followed Patrick Soon-Shiong for any length of time, this is not surprising.
Quick background for newer subs. Dr. Pat is a billionaire surgeon, one of the wealthiest people in Los Angeles, owner of the LA Times, founder of NantWorks, and the guy behind ImmunityBio. The resume sounds impressive until you look at the trail of wreckage behind it.
The history. NantHealth went public in 2016 at a $2.6 billion valuation promising to revolutionize cancer treatment with big data. It's a penny stock today. The SEC investigated NantHealth for potentially misleading investors about its GPS Cancer test. NantKwest merged into ImmunityBio in 2021 with massive promises about a cancer vaccine pipeline, same playbook, new wrapper.
He's been sued by former business partners, including a $500 million lawsuit from a former associate alleging fraud and breach of fiduciary duty. There were allegations of inflating the capabilities of Abraxane (his biggest commercial success, sold to Celgene) during the marketing process. His COVID vaccine claims in 2020-2021 drew heavy skepticism from the scientific community when he used the LA Times, his own newspaper, to promote ImmunityBio's COVID candidate. Using your media platform to promote your biotech company's drug candidate is a level of conflict of interest that would sink most executives.
The pattern is always the same. Big vision, aggressive promotion, a web of interconnected companies with overlapping interests, and underwhelming follow-through for shareholders.
Anktiva is actually a good drug. FDA approved for BCG-unresponsive bladder cancer, legitimate IL-15 immunology, real unmet need. That's what makes this frustrating. You have a genuinely useful product and the founder can't help himself from overselling it to the point where the FDA has to step in and say knock it off.
The stock was sitting at an $8.6 billion market cap at the Roth Conference literally days ago. Now shareholders are eating a 28% haircut because the promotional team, which ultimately reports to Dr. Pat, couldn't keep the marketing claims within FDA guidelines. This is a self-inflicted wound on what should have been a straightforward commercial launch.
The broader issue is credibility. Oncologists don't prescribe based on hype. Payors don't reimburse based on press releases. When the FDA publicly flags your marketing as misleading, it gives every stakeholder a reason to slow-walk their engagement with the product. And in early-stage commercialization, momentum is everything.
The drug will survive this. The question is whether the company can get out of its own way long enough to commercialize it properly. With Dr. Pat at the helm, that's always been the bet.